Modification Effects of Organic Solvents on Microenvironment of the Enzyme in Thermolysin - catalyzed Peptide Synthesis of N - ( Benzyloxycarbonyl ) - L - phenylalanyl - L - phenylalanine Methyl Ester
نویسنده
چکیده
L-phenyta}anine methy] ester (Phe-OMe) as substrates was dene mainly in a water-organic one phase solvent system. The organic so]yent content used was less than the saturatien concentration in buffer. With organic solvents with high logP ya]ues, the enzymatic actiyity increased as the organic solyent content increased; but further increases in the organic solvent content decreased the enzymatic activity, showing an "organic
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Enzymatic catalysis of formation of Z-aspartame in ionic liquid - An alternative to enzymatic catalysis in organic solvents.
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